Ipilimumab/Nivolumab
Hypophysitis, secondary adrenal insufficiency, secondary hypothyroidism, secondary hypogonadism, acute psychosis, and type 1 diabetes with diabetic ketoacidosis: 22 case reports-
Serious
An event is determined to be serious (based on the ICH definition) when the patient outcome is:
death
life-threatening
hospitalisation
disability
congenital anomaly
other medically important event