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PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes: A Double-Blind, Active and Placebo Controlled Study of Aggrenox vs. Clopidogrel, With and Without Micardis.

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Trial Profile

PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes: A Double-Blind, Active and Placebo Controlled Study of Aggrenox vs. Clopidogrel, With and Without Micardis.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 06 Sep 2023

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At a glance

  • Drugs Aspirin/dipyridamole (Primary) ; Telmisartan (Primary) ; Aspirin; Clopidogrel
  • Indications Embolism and thrombosis; Stroke
  • Focus Pharmacodynamics; Therapeutic Use
  • Acronyms PRoFESS
  • Sponsors Boehringer Ingelheim Pharmaceuticals

    • Most Recent Events

    • 26 Jul 2021 Results (n=37087) of pooled individual patient data from 6 randomized clinical trials (CAPRIE, ESPS-2, MATCH, CHARISMA, ESPRIT and PRoFES) investigating antiplatelet therapy in the subacute or chronic phase after noncardioembolic transient ischemic attack or stroke, published in the Stroke.
    • 26 Jun 2012 Magnetic resonance imaging substudy results published in Stroke.
    • 30 Aug 2010 A late-breaking analysis reviewing 21 trials, including PROFESS, was presented at the European Society of Cardiology (ESC) Congress, according to a European Society of Cardiology media release.

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