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A Multi-center, Double-Blind, Randomized, Parallel Group Study to Evaluate the Effects of Two Different Doses of Losartan on Morbidity and Mortality in Patients With Symptomatic Heart Failure Intolerant of ACE Inhibitor Treatment

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Trial Profile

A Multi-center, Double-Blind, Randomized, Parallel Group Study to Evaluate the Effects of Two Different Doses of Losartan on Morbidity and Mortality in Patients With Symptomatic Heart Failure Intolerant of ACE Inhibitor Treatment

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 31 Jan 2023

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At a glance

  • Drugs Losartan (Primary)
  • Indications Heart failure
  • Focus Registrational; Therapeutic Use
  • Acronyms HEAAL
  • Sponsors Organon

    • Most Recent Events

    • 01 Jan 2023 Results assessing serum potassium of patients treated with different doses of Losartan, published in the Journal of Cardiac Failure
    • 29 May 2021 Results assessing efficacy and safety of high vs. low dose of losartan in men vs. women using Cox models and Machine Learning algorithms, published in the European Journal of Heart Failure
    • 27 Mar 2012 Results assessing the effects of treatment on renal function presented at the 61st Annual Scientific Session of the American College of Cardiology.

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