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A Randomized Trial of Adjuvant Chemotherapy With Standard Regimens, Cyclophosphamide, Methotrexate and Fluorouracil - (CMF) or Doxorubicin and Cyclophosphamide - (AC), Versus Capecitabine in Women 65 Years and Older With Node Positive or Node-Negative Breast Cancer.

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Trial Profile

A Randomized Trial of Adjuvant Chemotherapy With Standard Regimens, Cyclophosphamide, Methotrexate and Fluorouracil - (CMF) or Doxorubicin and Cyclophosphamide - (AC), Versus Capecitabine in Women 65 Years and Older With Node Positive or Node-Negative Breast Cancer.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 20 May 2022

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At a glance

  • Drugs Capecitabine (Primary) ; Cyclophosphamide; Cyclophosphamide; Doxorubicin; Fluorouracil; Methotrexate
  • Indications Adenocarcinoma; Early breast cancer
  • Focus Therapeutic Use

Most Recent Events

  • 13 Apr 2022 Results pooled analysis of NCT00005970, NCT00024102, evaluating Role of age, BMI, and tumor subtype in racial/ethnic disparities in breast cancer survival, presented at the 113th Annual Meeting of the American Association for Cancer Research
  • 14 Dec 2019 Results (N= 15,457), a metanalysis of prospective randomized trials assessing efficacy of Capecitabine as a part of neo adjuvant or adjuvant therapy in patients with early breast cancer, presented at the 42nd Annual San Antonio Breast Cancer Symposium
  • 24 Jul 2019 Results (n=633) published in the Journal of Clinical Oncology.

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