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Randomized, Phase II, Open-Label Controlled Study of Two Different Doses and Schedules of EMD 72000 (Matuzumab) in Combination With Pemetrexed, or Pemetrexed Alone, as Second-Line Treatment for Stage IIIB/IV Non-Small Cell Lung Cancer and Progressive Disease on or After First-Line Treatment With a Platinum in Combination With Taxanes, Gemcitabine and Vinorelbine

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Trial Profile

Randomized, Phase II, Open-Label Controlled Study of Two Different Doses and Schedules of EMD 72000 (Matuzumab) in Combination With Pemetrexed, or Pemetrexed Alone, as Second-Line Treatment for Stage IIIB/IV Non-Small Cell Lung Cancer and Progressive Disease on or After First-Line Treatment With a Platinum in Combination With Taxanes, Gemcitabine and Vinorelbine

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Matuzumab (Primary) ; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Biomarker; Therapeutic Use
  • Sponsors EMD Pharmaceuticals; EMD Serono

    • Most Recent Events

    • 01 Nov 2010 Primary endpoint 'Objective-clinical-response-rate' has not been met, according to Journal of Thoracic Oncology publication.
    • 01 Nov 2010 Results were published in the Journal of Thoracic Oncology.
    • 13 Oct 2009 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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