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An Open-Label Multicenter Randomized Phase 3 Study Comparing the Combination of Doxil/Caelyx and Yondelis to Doxil/Caelyx Alone in Subjects With Advanced Relapsed Ovarian Cancer

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Trial Profile

An Open-Label Multicenter Randomized Phase 3 Study Comparing the Combination of Doxil/Caelyx and Yondelis to Doxil/Caelyx Alone in Subjects With Advanced Relapsed Ovarian Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Oct 2021

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At a glance

  • Drugs Trabectedin (Primary) ; Dexamethasone; Doxorubicin liposomal
  • Indications Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Sponsors Johnson & Johnson

    • Most Recent Events

    • 24 May 2017 Results comparing Trabectedin-Based Versus Platinum-Based Treatment in Relapsed, Partially Platinum Sensitive Ovarian Cancer patients from two randomised trials (OVA-301 and CALYPSO) presented at the 22nd Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research
    • 31 Oct 2016 Data from this trial presented at 16th Biennial International Gynecologic Cancer Society Meeting (IGCS), as per PharmaMar media release.
    • 30 May 2014 Results on overall survival from platinum-resistant patients retreated with platinum after OVA301 presented at the 50th Annual Meeting of the American Society of Clinical Oncology.

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