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Phase I Trial and Pharmacokinetic Study of Tariquidar (XR9576), A P-Glycoprotein Inhibitor, in Combination With Doxorubicin, Vinorelbine or Docetaxel in Pediatric Patients With Refractory Solid Tumors Including Brain Tumors.

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Trial Profile

Phase I Trial and Pharmacokinetic Study of Tariquidar (XR9576), A P-Glycoprotein Inhibitor, in Combination With Doxorubicin, Vinorelbine or Docetaxel in Pediatric Patients With Refractory Solid Tumors Including Brain Tumors.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Tariquidar (Primary) ; Docetaxel; Doxorubicin; Filgrastim; Vinorelbine
  • Indications Brain cancer; Ewing's sarcoma; Germ cell and embryonal neoplasms; Germ cell cancer; Liver cancer; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Soft tissue sarcoma; Wilms' tumour
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 29 Sep 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 29 Sep 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 04 Jun 2007 Status changed from recruiting to in progress.

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