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A Phase 2 Study Incorporating Bone Marrow Microenvironment (ME) Co-Targeting Bortezomib Into Tandem Melphalan-Based Autotransplants With DT PACE for Induction/Consolidation and Thalidomide + Dexamethasone for maintenance

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Trial Profile

A Phase 2 Study Incorporating Bone Marrow Microenvironment (ME) Co-Targeting Bortezomib Into Tandem Melphalan-Based Autotransplants With DT PACE for Induction/Consolidation and Thalidomide + Dexamethasone for maintenance

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Jul 2023

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At a glance

  • Drugs Bortezomib (Primary) ; Cisplatin; Cyclophosphamide; Dexamethasone; Doxorubicin; Etoposide; Melphalan; Thalidomide
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms Total Therapy III
  • Most Recent Events

    • 06 Jun 2023 Results assessing follow up of MM trials (TT1 (NCT00580372), TT2 (NCT00083551), TT3a (NCT00081939) and TT3b (NCT00572169)) and reporting to date with RSRs to assess for curability,resented at the 59th Annual Meeting of the American Society of Clinical Oncology.
    • 07 Dec 2007 Status changed from recruiting to in progress.
    • 02 Sep 2005 New trial record.

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