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A Randomized, Multicenter, Double-Blind, Placebo-Controlled, 2-Arm, Phase III Study of Oral GW572016 [lapatinib] in Combination With Paclitaxel in Subjects Previously Untreated or Advanced or Metastatic Breast Cancer

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Trial Profile

A Randomized, Multicenter, Double-Blind, Placebo-Controlled, 2-Arm, Phase III Study of Oral GW572016 [lapatinib] in Combination With Paclitaxel in Subjects Previously Untreated or Advanced or Metastatic Breast Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Jul 2023

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At a glance

  • Drugs Lapatinib (Primary) ; Paclitaxel
  • Indications Advanced breast cancer
  • Focus Biomarker; Registrational; Therapeutic Use
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 25 Jan 2016 Results of pooled analysis (n=1902) from this and two other trials (see profile 1432 and 1409) published in the Journal of Clinical Oncology
    • 03 Jun 2014 Results (meta-analysis) presented at the 50th Annual Meeting of the American Society of Clinical Oncology.
    • 22 Jan 2010 QOL results published in the Current Medical Research and Opinion : 22 Jan 2010

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