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COG 1952 A Randomized Comparison of Oral Mercaptopurine vs. Oral Thioguanine and Intrathecal Methotrexate vs. Intrathecal Methotrexate/Cytarabine/Hydrocortisone for Standard Risk Acute Lymphoblastic Leukemia - A Phase III, Group Wide Study - CCG-1952.

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Trial Profile

COG 1952 A Randomized Comparison of Oral Mercaptopurine vs. Oral Thioguanine and Intrathecal Methotrexate vs. Intrathecal Methotrexate/Cytarabine/Hydrocortisone for Standard Risk Acute Lymphoblastic Leukemia - A Phase III, Group Wide Study - CCG-1952.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Antineoplastics; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Hydrocortisone; Mercaptopurine; Methotrexate; Pegaspargase; Prednisone; Tioguanine; Vincristine
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use
  • Most Recent Events

    • 09 Feb 2017 Biomarkers information updated
    • 01 Feb 2010 Results, with respect to tioguanine versus mercaptopurine, published in Blood.
    • 05 Oct 2009 New source identified and integrated (New Jersey Cancer Trial Connect record no. COG1952).

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