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A Phase III Study to Evaluate Letrozole as Adjuvant Endocrine Therapy for Postmenopausal Women With Receptor (ER and/or PgR) Positive Tumors.

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Trial Profile

A Phase III Study to Evaluate Letrozole as Adjuvant Endocrine Therapy for Postmenopausal Women With Receptor (ER and/or PgR) Positive Tumors.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 19 Aug 2022

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At a glance

  • Drugs Letrozole (Primary) ; Tamoxifen
  • Indications Adenocarcinoma; Ductal carcinoma; Early breast cancer; HER2 negative breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms BIG 1-98

    • Most Recent Events

    • 04 Jun 2019 Results of sub group analysis (n=911) assessing post-DR survival, presented at the 55th Annual Meeting of the American Society of Clinical Oncology.
    • 26 Nov 2018 Results of long term follow up of BIG 1-98 trial published in the Journal of Clinical Oncology
    • 08 Dec 2017 Status changed from active, no longer recruiting to completed.

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