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A Phase I Dose Escalation Study of MK0457 [VX 680, tozasertib] Evaluating the Safety Tolerability, Pharmacokinetics and Pharmacodynamics of a 24-Hour Continuous Infusion Given Every 21 Days in Patients With Advanced Cancer

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A Phase I Dose Escalation Study of MK0457 [VX 680, tozasertib] Evaluating the Safety Tolerability, Pharmacokinetics and Pharmacodynamics of a 24-Hour Continuous Infusion Given Every 21 Days in Patients With Advanced Cancer

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 12 May 2022

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At a glance

  • Drugs Tozasertib (Primary)
  • Indications Cancer; Solid tumours
  • Focus Adverse reactions; Biomarker
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 15 Jan 2008 The expected completion date for this trial is now 1 Nov 2007.
    • 22 Dec 2007 Patient numbers, completion date and official title changed as per ClinicalTrials.gov.
    • 19 Nov 2007 Status change from recruiting to terminated.

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