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The Value of Dexamethasone Versus Prednisolone During Induction and Maintenance Therapy of Prolonged Versus Conventional Duration of L-Asparaginase Therapy During Consolidation and Late Intensification, and of Corticosteroid + VCR Pulses During Maintenance in Acute Lymphoblastic Leukemia and Lymphoblastic Non-Hodgkin Lymphoma of Childhood.

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Trial Profile

The Value of Dexamethasone Versus Prednisolone During Induction and Maintenance Therapy of Prolonged Versus Conventional Duration of L-Asparaginase Therapy During Consolidation and Late Intensification, and of Corticosteroid + VCR Pulses During Maintenance in Acute Lymphoblastic Leukemia and Lymphoblastic Non-Hodgkin Lymphoma of Childhood.

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Asparaginase; Cyclophosphamide; Cytarabine; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Etoposide; Folinic acid; Hydrocortisone; Mercaptopurine; Methotrexate; Methotrexate; Methotrexate; Methylprednisolone; Mitoxantrone; Prednisolone; Tioguanine; Vincristine; Vindesine
  • Indications Non-Hodgkin's lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Pharmacokinetics; Therapeutic Use
  • Most Recent Events

    • 21 Jan 2011 Biomarkers information updated
    • 21 Jun 2010 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov record.
    • 27 May 2010 Results from the maintenance treatment phase have been published in Blood : 20 Apr 2010. Available from: URL: http://dx.doi.org/10.1182/blood-2009-10-247965.
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