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Phase II study of methotrexate, mechlorethamine [chlormethine], vincristine, prednisone, and procarbazine (MMOPP) as primary therapy in infants or young children with primitive neuroectodermal tumors or high-grade astrocytoma.

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Trial Profile

Phase II study of methotrexate, mechlorethamine [chlormethine], vincristine, prednisone, and procarbazine (MMOPP) as primary therapy in infants or young children with primitive neuroectodermal tumors or high-grade astrocytoma.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Feb 2013

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At a glance

  • Drugs Chlormethine (Primary) ; Methotrexate (Primary) ; Prednisone (Primary) ; Procarbazine (Primary) ; Vincristine (Primary) ; Folinic acid
  • Indications Astrocytoma; Brain cancer; Ependymoma; Medulloblastoma; Neuroectodermal tumours
  • Focus Therapeutic Use

    • Most Recent Events

    • 02 Jul 2010 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 02 Jul 2010 Actual end date (Jan 2008) added as reported by ClinicalTrials.gov.
    • 26 Sep 2005 New trial record.

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