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A phase III trial of CHOP [cyclophosphamide, doxorubicin, vincristine and prednisone] plus rituximab vs CHOP plus iodine-131-labeled monoclonal anti-B1 antibody (tositumomab) for treatment of newly diagnosed follicular non-Hodgkin's lymphomas

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A phase III trial of CHOP [cyclophosphamide, doxorubicin, vincristine and prednisone] plus rituximab vs CHOP plus iodine-131-labeled monoclonal anti-B1 antibody (tositumomab) for treatment of newly diagnosed follicular non-Hodgkin's lymphomas

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 08 Jul 2024

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At a glance

  • Drugs Iodine-131 tositumomab (Primary) ; Rituximab (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Vincristine
  • Indications Follicular lymphoma; Non-Hodgkin's lymphoma
  • Focus Therapeutic Use

    • Most Recent Events

    • 24 Jun 2024 Planned End Date changed from 1 Mar 2024 to 1 Mar 2025.
    • 31 May 2024 According to an Adaptive Biotechnologies media release, results from this trial, to be presented at the European Hematology Association (EHA) Hybrid Congress taking place June 13-16 in Madrid and virtually.
    • 12 Dec 2023 Results discussing MRD analysis by ClonoSeq assay predicts outcomes in a prospective cohort of patients with advanced stage FL, presented at the 65th American Society of Hematology Annual Meeting and Exposition

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