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Phase II Two Arm Trial of the Proteasome Inhibitor, PS-341 (Velcade TM) in Combination With Irinotecan or PS-341 Alone Followed by the Addition of Irinotecan at Time of Progression in Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

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Trial Profile

Phase II Two Arm Trial of the Proteasome Inhibitor, PS-341 (Velcade TM) in Combination With Irinotecan or PS-341 Alone Followed by the Addition of Irinotecan at Time of Progression in Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Bortezomib (Primary) ; Irinotecan
  • Indications Head and neck cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 30 Jun 2009 New source identified and integrated (New Jersey Cancer Trial Connect).
    • 30 Jun 2009 Additional lead trial investigator identified as reported by New Jersey Cancer Trial Connect.
    • 02 Jun 2009 Interim results from 62 (of 71 enrolled) patients were presented at ASCO 2009.

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