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Phase II Two Arm Trial of the Proteasome Inhibitor, PS-341 (Velcade TM) in Combination With Irinotecan or PS-341 Alone Followed by the Addition of Irinotecan at Time of Progression in Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Trial Profile

Phase II Two Arm Trial of the Proteasome Inhibitor, PS-341 (Velcade TM) in Combination With Irinotecan or PS-341 Alone Followed by the Addition of Irinotecan at Time of Progression in Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Bortezomib (Primary) ; Irinotecan
  • Indications Head and neck cancer
  • Focus Therapeutic Use

Most Recent Events

  • 30 Jun 2009 New source identified and integrated (New Jersey Cancer Trial Connect).
  • 30 Jun 2009 Additional lead trial investigator identified as reported by New Jersey Cancer Trial Connect.
  • 02 Jun 2009 Interim results from 62 (of 71 enrolled) patients were presented at ASCO 2009.

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