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A phase III protocol of androgen suppression (AS) and radiation therapy (RT) vs AS and RT followed by chemotherapy with paclitaxel, estramustine, and etoposide for localized, high-risk, prostate cancer

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A phase III protocol of androgen suppression (AS) and radiation therapy (RT) vs AS and RT followed by chemotherapy with paclitaxel, estramustine, and etoposide for localized, high-risk, prostate cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Estramustine (Primary) ; Etoposide (Primary) ; Paclitaxel (Primary) ; Antiandrogens; Antineoplastics; Bicalutamide; Flutamide; Gonadotropin releasing hormone stimulants; Goserelin; Leuprorelin; LHRH receptor agonists
  • Indications Prostate cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 06 Jun 2017 Results of a secondary analysis by post-radiation PSA status to identify patients that benefit from treatment intensification (n=333), presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
    • 13 Nov 2013 New source identified and integrated (M.D. Anderson Cancer Center, RTOG99-02).
    • 08 Jun 2010 Efficacy results have been presented at ASCO 2010.

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