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A Randomized, Multi-Center Phase III Trial of Irinotecan in Combination With Three Different Methods of Administration of Fluoropyrimidine: Infusional 5-FU (FOLFIRI), Modified-Bolus 5-FU (Day 1 and 8), and Oral Capecitabine (Day 1-14); With Celecoxib Versus Placebo as First-Line Treatment for Patients With Metastatic Colorectal Cancer Study Amended April 23, 2004 to Include Bevacizumab

Trial Profile

A Randomized, Multi-Center Phase III Trial of Irinotecan in Combination With Three Different Methods of Administration of Fluoropyrimidine: Infusional 5-FU (FOLFIRI), Modified-Bolus 5-FU (Day 1 and 8), and Oral Capecitabine (Day 1-14); With Celecoxib Versus Placebo as First-Line Treatment for Patients With Metastatic Colorectal Cancer Study Amended April 23, 2004 to Include Bevacizumab

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Feb 2010

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At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine (Primary) ; Celecoxib (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary)
  • Indications Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms BICC-C
  • Most Recent Events

    • 20 Oct 2007 Results published in JCO.
    • 03 Oct 2005 New trial record.
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