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Randomized, controlled, open label, multi-center phase III trial comparing the safety and antiviral activity of a protease-containing regimen (d4T/ddI/IDV/RTV) [stavudine + didanosine + indinavir + ritonavir] versus a protease-sparing regimen (d4T/ddI/EFV) [stavudine + didanosine + efavirenz] and the ability of interleukin-2 to purge HIV from latent stores in patients with acute/early HIV infection

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Trial Profile

Randomized, controlled, open label, multi-center phase III trial comparing the safety and antiviral activity of a protease-containing regimen (d4T/ddI/IDV/RTV) [stavudine + didanosine + indinavir + ritonavir] versus a protease-sparing regimen (d4T/ddI/EFV) [stavudine + didanosine + efavirenz] and the ability of interleukin-2 to purge HIV from latent stores in patients with acute/early HIV infection

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Efavirenz (Primary) ; Indinavir (Primary) ; Ritonavir (Primary) ; Abacavir; Didanosine; Interleukin-2; Stavudine
  • Indications HIV infections
  • Focus Therapeutic Use
  • Most Recent Events

    • 04 Sep 2013 Status changed from not yet recruiting to completed as reported by ClinicalTrials.gov.
    • 28 Sep 2008 Planned initiation date (Sep 2009) added as reported by CT.gov
    • 28 Sep 2008 Planned end date (Sep 2010) added as reported by CT.gov

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