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A phase II/III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to evaluate the safety and efficacy of rituximab in adults with primary progressive multiple sclerosis

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Trial Profile

A phase II/III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to evaluate the safety and efficacy of rituximab in adults with primary progressive multiple sclerosis

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 07 Apr 2022

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At a glance

  • Drugs Rituximab (Primary)
  • Indications Multiple sclerosis
  • Focus Therapeutic Use
  • Acronyms OLYMPUS
  • Sponsors Genentech

    • Most Recent Events

    • 26 Feb 2022 Results using data from ORATORIO, OLYMPUS and ARPEGGIO; predicting the conditional average treatment effect for individuals taking anti-CD20 monoclonal antibodies and laquinimod by using deep learning, presented at the Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2022
    • 01 Oct 2009 Results published in Annals of Neurology.
    • 12 May 2009 Actual end date (Feb 2009) added as reported by ClinicalTrials.gov.

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