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A Phase III, Randomized, Open-Label Trial to Evaluate Strategies for Providing Antiretroviral Therapy to Infants Shortly After Primary Infection in a Resource Poor Setting.

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A Phase III, Randomized, Open-Label Trial to Evaluate Strategies for Providing Antiretroviral Therapy to Infants Shortly After Primary Infection in a Resource Poor Setting.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 31 Aug 2023

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At a glance

  • Drugs Abacavir (Primary) ; Didanosine (Primary) ; Efavirenz (Primary) ; Lamivudine (Primary) ; Lopinavir/ritonavir (Primary) ; Nevirapine (Primary) ; Zidovudine (Primary)
  • Indications HIV infections; HIV-1 infections
  • Focus Adverse reactions; Pharmacodynamics; Therapeutic Use
  • Acronyms CHER; CIPRA-SA-2; CIPRA-ZA-2

    • Most Recent Events

    • 15 Feb 2020 Results (n=579) assessing effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines from two clinical trials: NCT00099658 and NCT00102960 were published in the Vaccine
    • 01 Sep 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 11 Aug 2009 Planned number of patients changed from 417 to 451 as reported by ClinicalTrials.gov.

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