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A phase IV randomized, multicenter, open-label study to compare the safety, tolerability and efficacy of Trizivir (abacavir 300mg, lamivudine 150mg, and zidovudine 300mg) bid vs Combivir (lamivudine 150mg and zidovudine 300mg) bid plus atazanavir 400mg qd in antiretroviral naive HIV-1 infected subjects over 48 weeks.

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Trial Profile

A phase IV randomized, multicenter, open-label study to compare the safety, tolerability and efficacy of Trizivir (abacavir 300mg, lamivudine 150mg, and zidovudine 300mg) bid vs Combivir (lamivudine 150mg and zidovudine 300mg) bid plus atazanavir 400mg qd in antiretroviral naive HIV-1 infected subjects over 48 weeks.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 17 Jul 2023

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At a glance

  • Drugs Atazanavir (Primary) ; Lamivudine/zidovudine (Primary) ; Lamivudine/zidovudine/abacavir (Primary)
  • Indications HIV-1 infections
  • Focus Therapeutic Use
  • Acronyms ACTION
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 15 Oct 2008 Actual start date changed from May 2004 to Apr 2004 as reported by Clinicaltrials.gov
    • 17 Jul 2007 Status change from in progress to completed
    • 19 Oct 2005 New trial record.

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