A multicenter, double-blind, randomized, placebo-controlled study to evaluate the effects of ezetimibe + simvastatin on clinical outcomes in patients with aortic stenosis.

Trial Profile

A multicenter, double-blind, randomized, placebo-controlled study to evaluate the effects of ezetimibe + simvastatin on clinical outcomes in patients with aortic stenosis.

Completed
Phase of Trial: Phase III

Latest Information Update: 25 Dec 2017

At a glance

  • Drugs Ezetimibe/simvastatin (Primary)
  • Indications Aortic valve stenosis; Atrial fibrillation; Cardiovascular disorders; Heart failure; Ischaemic heart disorders
  • Focus Registrational; Therapeutic Use
  • Acronyms SEAS
  • Sponsors Merck & Co
  • Most Recent Events

    • 25 Dec 2017 Results of post-hoc analysis published in the American Journal of Cardiology
    • 11 Jul 2017 Results (n=1725) of post hoc analysis assessing sex differences in risk factors of aortic valve calcification, published in the Heart
    • 28 Apr 2017 Results of association of stroke volume and cardiovascular events (n=1671) published in the Heart
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