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An open-label, non-randomized study of pharmacokinetic interactions between depo-medroxyprogesterone acetate (DMPA, Depo-Provera) and selected protease inhibitor (PI) and nonnucleoside reverse transcriptase inhibitor (NNRTI) therapies among HIV-infected women

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Trial Profile

An open-label, non-randomized study of pharmacokinetic interactions between depo-medroxyprogesterone acetate (DMPA, Depo-Provera) and selected protease inhibitor (PI) and nonnucleoside reverse transcriptase inhibitor (NNRTI) therapies among HIV-infected women

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Medroxyprogesterone (Primary) ; Antiretrovirals; Efavirenz; HIV protease inhibitors; Indinavir; Nelfinavir; Nevirapine; Non-nucleoside reverse transcriptase inhibitors; Ritonavir
  • Indications HIV infections; HIV-1 infections; Pregnancy
  • Focus Pharmacokinetics

    • Most Recent Events

    • 20 Jun 2021 Results of a population pharmacokinetic analysis of data pooled from three ACTG studies (A5093, A5283 and A5338) published in the Clinical Pharmacology and Therapeutics
    • 21 Oct 2005 New trial record.

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