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A multicenter, double-blind, randomized study to evaluate the safety and efficacy of the addition of MK-0431 compared with sulfonylurea therapy in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin monotherapy

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Trial Profile

A multicenter, double-blind, randomized study to evaluate the safety and efficacy of the addition of MK-0431 compared with sulfonylurea therapy in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin monotherapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 May 2022

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At a glance

  • Drugs Sitagliptin (Primary) ; Glipizide; Metformin
  • Indications Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.

    • Most Recent Events

    • 13 Jun 2019 Trial has been completed in Spain, Denmark and UK according to European Clinical Trials Database record.
    • 08 Feb 2014 Results published in the Drugs and Aging.
    • 29 Jun 2010 Positive results from post-hoc analysis on the composite endpopint of lower blood sugar, no hypglycemia and no weight gain presented at the American Diabetes Association 70th Annual Scientific Sessions (ADA 2010).

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