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CONCEPT - Phase IV, Randomized, Prospective, Multicenter Comparison of Intermittent Schedule of Oxaliplatin Combined With FOLFOX/Bevacizumab vs Conventional Mode of Administration of FOLFOX [fluorouracil + folinic acid + oxaliplatin]/bevacizumab [Avastin] versus the Conventional Mode of Administration of FOLFOX/Bevacizumab + Neuroprophylaxis With Calcium/Magnesium for Optimization of First-Line Therapy of Metastatic Colorectal Cancer.

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CONCEPT - Phase IV, Randomized, Prospective, Multicenter Comparison of Intermittent Schedule of Oxaliplatin Combined With FOLFOX/Bevacizumab vs Conventional Mode of Administration of FOLFOX [fluorouracil + folinic acid + oxaliplatin]/bevacizumab [Avastin] versus the Conventional Mode of Administration of FOLFOX/Bevacizumab + Neuroprophylaxis With Calcium/Magnesium for Optimization of First-Line Therapy of Metastatic Colorectal Cancer.

Status: Discontinued
Phase of Trial: Phase IV

Latest Information Update: 07 Apr 2014

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At a glance

  • Drugs Oxaliplatin (Primary) ; Bevacizumab; Calcium gluconate; Fluorouracil; Folinic acid; Magnesium sulfate
  • Indications Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms CONCEPT

    • Most Recent Events

    • 07 Mar 2014 Results published in the Annals of Oncology.
    • 30 Jul 2007 Drug interaction leading to discontinuation reported in the Journal of Clinical Oncology.
    • 16 Jul 2007 Status changed from in progress to discontinued.

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