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Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome: A Randomized Placebo-Controlled Trial Evaluating the Clinical Benefits of Early Front-Loaded Eptifibatide in the Treatment of Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS)

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Trial Profile

Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome: A Randomized Placebo-Controlled Trial Evaluating the Clinical Benefits of Early Front-Loaded Eptifibatide in the Treatment of Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Feb 2022

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At a glance

  • Drugs Eptifibatide (Primary) ; Aspirin; Heparin; Low molecular weight heparins
  • Indications Acute coronary syndromes; Myocardial ischaemia
  • Focus Biomarker; Therapeutic Use
  • Acronyms EARLY-ACS
  • Sponsors Merck Sharp & Dohme; Schering-Plough

    • Most Recent Events

    • 28 Jan 2020 Results of post hoc, subanalysis, in the EARLY ACS, exploring the association between morphine and ischemic events (n=5,438) in patients treated with concomitant clopidogrel, with Patients not treated with clopidogrel (n = 3,462) are used as negative controls,presenting with non-ST-segment elevation acute coronary syndromes (NSTEACS) published in the Journal of the American College of Cardiology
    • 09 Nov 2012 Planned number of patients changed from 9500 to 10500 as reported by European Clinical Trials Database record.
    • 30 Mar 2009 Results presented at the American College of Cardiology meeting and reported in the New England Journal of Medicine, as reported by Schering-Plough.

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