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A Multicenter, Double-Blind, Flexible-Dose, 6-Month Trial Comparing the Efficacy and Safety of Asenapine With Olanzapine in Stable Subjects With Predominant, Persistent Negative Symptoms of Schizophrenia.

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Trial Profile

A Multicenter, Double-Blind, Flexible-Dose, 6-Month Trial Comparing the Efficacy and Safety of Asenapine With Olanzapine in Stable Subjects With Predominant, Persistent Negative Symptoms of Schizophrenia.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 19 Aug 2024

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At a glance

  • Drugs Asenapine (Primary) ; Olanzapine
  • Indications Schizophrenia
  • Focus Therapeutic Use
  • Acronyms APHRODITE
  • Sponsors Merck Sharp & Dohme; Organon

    • Most Recent Events

    • 13 Jun 2019 Trial has been completed in UK and Spain.
    • 22 Dec 2011 Primary endpoint 'Positive-and-Negative-Syndrome-Scale' has not been met.
    • 17 Jan 2008 Status changed from recruiting to completed.

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