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A double-blind, randomized, placebo controlled, dose escalation, multi-center phase I/II trial of HuMax-CD20, a fully human monoclonal anti-CD20 antibody, in patients with active rheumatoid arthritis who have previously failed one or more DMARDs

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Trial Profile

A double-blind, randomized, placebo controlled, dose escalation, multi-center phase I/II trial of HuMax-CD20, a fully human monoclonal anti-CD20 antibody, in patients with active rheumatoid arthritis who have previously failed one or more DMARDs

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 Jul 2023

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At a glance

  • Drugs Ofatumumab (Primary)
  • Indications Rheumatoid arthritis
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 05 Nov 2013 The extension study has been discontinued as the sponsor is no longer developing IV ofatumumab for rheumatoid arthritis, according to the Clinicaltrials.gov record.
    • 28 Jul 2011 New source identified and integrated (European ClinicalTrials Database).
    • 21 Jan 2009 GlaxoSmithKline reported as trial sponsor, and patient inclusions updated from ClinicalTrials.gov.
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