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A phase I clinical trial to evaluate the safety and immunogenicity of a clade B Gag DNA/PLG and Env DNA/PLG microparticles vaccine and a Clade B recombinant, oligomeric gp140/MF59 adjuvant vaccine in healthy, HIV-1 uninfected adult participants.

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Trial Profile

A phase I clinical trial to evaluate the safety and immunogenicity of a clade B Gag DNA/PLG and Env DNA/PLG microparticles vaccine and a Clade B recombinant, oligomeric gp140/MF59 adjuvant vaccine in healthy, HIV-1 uninfected adult participants.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs HIV DNA vaccine; HIV vaccine; MF 59
  • Indications HIV-1 infections
  • Focus Adverse reactions; Pharmacodynamics

    • Most Recent Events

    • 04 May 2012 Biomarkers information updated
    • 03 May 2012 Actual end date (Sep 2007) added as reported by ClinicalTrials.gov.
    • 01 Apr 2011 Results published in the Journal of Infectious Diseases.

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