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A twenty six-week, randomized, double-blind, parallel group, multicenter, active controlled, dose titration study to evaluate the efficacy and safety of aliskiren compared to HCTZ [hydrochlorothiazide] with the optional addition of amlodipine, followed by a second twenty six weeks of blinded treatment, in patients with essential hypertension.

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A twenty six-week, randomized, double-blind, parallel group, multicenter, active controlled, dose titration study to evaluate the efficacy and safety of aliskiren compared to HCTZ [hydrochlorothiazide] with the optional addition of amlodipine, followed by a second twenty six weeks of blinded treatment, in patients with essential hypertension.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 29 Dec 2014

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At a glance

  • Drugs Aliskiren (Primary) ; Amlodipine; Hydrochlorothiazide
  • Indications Essential hypertension; Hypertension
  • Focus Registrational; Therapeutic Use
  • Sponsors Novartis

    • Most Recent Events

    • 07 Nov 2011 Actual end date (July 2006) added as reported by ClinicalTrials.gov (Extension trial: NCT00294710).
    • 07 Nov 2011 Actual end date (July 2006) added as reported by ClinicalTrials.gov (Extension trial: NCT00294710).
    • 05 Nov 2005 New trial record.

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