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A twelve-week, randomized, double-blind, multi-center, placebo controlled, parallel group study to evaluate the safety and efficacy of aliskiren 150 mg when added to standard therapy in hypertensive patients with stable heart failure.

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Trial Profile

A twelve-week, randomized, double-blind, multi-center, placebo controlled, parallel group study to evaluate the safety and efficacy of aliskiren 150 mg when added to standard therapy in hypertensive patients with stable heart failure.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Aliskiren (Primary)
  • Indications Essential hypertension; Heart failure; Hypertension
  • Focus Adverse reactions; Registrational
  • Acronyms ALOFT; ASPIRE-HIGHER
  • Sponsors Novartis
  • Most Recent Events

    • 04 Apr 2011 Subanalysis results published in the European Journal of Heart Failure.
    • 16 Mar 2010 Results were presented at the 59th Annual Scientific Session of the American College of Cardiology.
    • 02 Sep 2007 Results have been presented.

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