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A Randomized Phase 2 Trial of Doxorubicin Plus Pemetrexed Followed by Docetaxel, Versus Doxorubicin Plus Cyclophosphamide Followed by Docetaxel, as Neoadjuvant Treatment for Early Breast Cancer. [STUDIO RANDOMIZZATO DI FASE II DI CONFRONTO TRA DOXORUBICINA + PEMETREXED SEGUITO DA DOCETAXEL VERSUS DOXORUBICINA + CICLOFOSFAMIDE SEGUITO DA DOCETAXEL, COME TRATTAMENTO NEOADIUVANTE DEL TUMORE DELLA MAMMELLA IN STADIO INIZIALE]

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Trial Profile

A Randomized Phase 2 Trial of Doxorubicin Plus Pemetrexed Followed by Docetaxel, Versus Doxorubicin Plus Cyclophosphamide Followed by Docetaxel, as Neoadjuvant Treatment for Early Breast Cancer. [STUDIO RANDOMIZZATO DI FASE II DI CONFRONTO TRA DOXORUBICINA + PEMETREXED SEGUITO DA DOCETAXEL VERSUS DOXORUBICINA + CICLOFOSFAMIDE SEGUITO DA DOCETAXEL, COME TRATTAMENTO NEOADIUVANTE DEL TUMORE DELLA MAMMELLA IN STADIO INIZIALE]

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Oct 2021

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Docetaxel (Primary) ; Doxorubicin (Primary) ; Pemetrexed (Primary)
  • Indications Early breast cancer
  • Focus Pharmacogenomic; Therapeutic Use
  • Most Recent Events

    • 05 Jun 2012 Results at 3 years presented at the 48th Annual Meeting of the American Society of Clinical Oncology.
    • 04 Jun 2010 Analysis investigating the correlation between the CD24 ala/val polymorphism and the pathological complete response at the 46th Annual Meeting of the American Society of Clinical Oncology.
    • 31 May 2009 Results were presented at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO).

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