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Peginterferon alfa-2a and ribavirin combination therapy in patients with HBeAg [hepatitis B envelope antigen]-negative chronic HBV [hepatitis B virus] infection (PARC Study)

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Trial Profile

Peginterferon alfa-2a and ribavirin combination therapy in patients with HBeAg [hepatitis B envelope antigen]-negative chronic HBV [hepatitis B virus] infection (PARC Study)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Peginterferon alfa-2a (Primary) ; Ribavirin (Primary)
  • Indications Hepatitis B
  • Focus Therapeutic Use
  • Acronyms PARC
  • Most Recent Events

    • 12 Nov 2020 Results of a pooled analysis of data pooled from 2 randomized trials (PARC and NCT00146705) the degree of on-treatment viral antigen decline among patients with pronounced HBV RNA decrease in relation to off-treatment sustained response and HBsAg loss published in the Alimentary Pharmacology and Therapeutics
    • 08 Jan 2020 Results, follow up and long term follow up at week 144 assessing the HBV-RNA levels during treatment can be associated with response, published in the Clinical Infectious Diseases
    • 11 May 2010 Results were published in the American Journal of Gastroenterology.

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