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A Randomized, Double-Blind, Trial of Anti-TNFa Chimeric Monoclonal Antibody (Infliximab) in Combination With Methotrexate Compared With Methotrexate Alone for the Treatment of Patients With Early Rheumatoid Arthritis

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Trial Profile

A Randomized, Double-Blind, Trial of Anti-TNFa Chimeric Monoclonal Antibody (Infliximab) in Combination With Methotrexate Compared With Methotrexate Alone for the Treatment of Patients With Early Rheumatoid Arthritis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Feb 2020

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At a glance

  • Drugs Infliximab (Primary) ; Methotrexate (Primary)
  • Indications Rheumatoid arthritis
  • Focus Therapeutic Use
  • Acronyms ASPIRE

    • Most Recent Events

    • 01 Oct 2016 Results of post-hoc analyses on clinical remission rates using data from infliximab (ASPIRE,ATTRACT) and golimumab (GO-FORWARD) trials, published in the Arthritis and Rheumatology.
    • 30 Mar 2010 Actual patient number (607) added as reported by ClinicalTrials.gov.
    • 20 Nov 2005 New trial record.

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