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A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients with Solid Tumors and in Combination with Temozolomide in Patients with Advanced and/or Metastatic Melanoma

Trial Profile

A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients with Solid Tumors and in Combination with Temozolomide in Patients with Advanced and/or Metastatic Melanoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Jun 2017

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At a glance

  • Drugs Lenvatinib (Primary) ; Temozolomide
  • Indications Lymphoma; Solid tumours
  • Focus Adverse reactions
  • Sponsors Eisai Inc

Most Recent Events

  • 31 May 2017 Results (n= 452) assessing optimal lenvatinib dose based on population PK and exposure-response analysis using using pooled data from NCT00946153, NCT00121719, NCT00121680, NCT00280397, NCT01268293 and other 8 phase 1 studies in healthy adults, published in the Journal of Clinical Pharmacology
  • 02 Jul 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
  • 27 Jan 2015 Planned primary completion date changed from 1 Nov 2011 to 1 Sep 2011, as reported by ClinicalTrials.gov.

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