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ONTARGET ONgoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial A Large, Simple Randomized Trial of an Angiotensin II Receptor Antagonist (Telmisartan) and an ACE-Inhibitor (Ramipril) in Patients at High Risk for Cardiovascular Events and TRANSCEND Telmisartan Randomized AssessmeNt Study in aCE iNtolerant Subjects With Cardiovascular Disease. A Parallel Study Comparing the Effects of Telmisartan With Placebo and Outcomes in Patients at High Risk for Cardiovascular Events and Intolerant to ACE-I

Trial Profile

ONTARGET ONgoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial A Large, Simple Randomized Trial of an Angiotensin II Receptor Antagonist (Telmisartan) and an ACE-Inhibitor (Ramipril) in Patients at High Risk for Cardiovascular Events and TRANSCEND Telmisartan Randomized AssessmeNt Study in aCE iNtolerant Subjects With Cardiovascular Disease. A Parallel Study Comparing the Effects of Telmisartan With Placebo and Outcomes in Patients at High Risk for Cardiovascular Events and Intolerant to ACE-I

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 09 Oct 2023

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At a glance

  • Drugs Telmisartan (Primary) ; Ramipril
  • Indications Angina pectoris; Cardiovascular disorders; Hypertension; Intermittent claudication; Left ventricular hypertrophy; Unstable angina pectoris
  • Focus Pharmacodynamics; Therapeutic Use
  • Acronyms TRANS; TRANSCEND
  • Sponsors Boehringer Ingelheim
  • Most Recent Events

    • 28 Mar 2019 Results of pooled post hoc analysis from ONTARGET/TRANSCEND studies assessing cardiovascular outcomes and achieved blood pressure published in the European Heart Journal.
    • 24 Dec 2018 Results assessing resting heart rate and cardiovascular outcomes in diabetic and non-diabetic individuals from ONTARGET and TRANSCEND trials, published in the European Heart Journal.
    • 01 Jul 2015 Results published in the Journal of Internal Medicine.
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