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Randomized study of ACVBP [doxorubicin + cyclophosphamide + vindesine + bleomycin + prednisone] versus ACVBP plus rituximab in previously untreated patients aged from 18 to 65 years with low-risk localized diffuse large B-cell lymphoma (Age-Adjusted IPI = 0).

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Trial Profile

Randomized study of ACVBP [doxorubicin + cyclophosphamide + vindesine + bleomycin + prednisone] versus ACVBP plus rituximab in previously untreated patients aged from 18 to 65 years with low-risk localized diffuse large B-cell lymphoma (Age-Adjusted IPI = 0).

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Rituximab (Primary) ; Bleomycin; Cyclophosphamide; Doxorubicin; Prednisone; Vindesine
  • Indications Diffuse large B cell lymphoma
  • Focus Therapeutic Use
  • Most Recent Events

    • 13 Mar 2017 Biomarkers information updated
    • 12 Dec 2012 Interim results published in Annals of Oncology.
    • 03 Mar 2011 Additional lead trial centers and investigators identified as reported by ClinicalTrials.gov.

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