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Phase 1 open label, dose escalating, multiple dose study to determine the safety, tolerability, maximum tolerated dose, and pharmacokinetics of MPC-6827 administered IV weekly X 3, repeated every 28 days, in subjects with refractory brain metastases.

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Trial Profile

Phase 1 open label, dose escalating, multiple dose study to determine the safety, tolerability, maximum tolerated dose, and pharmacokinetics of MPC-6827 administered IV weekly X 3, repeated every 28 days, in subjects with refractory brain metastases.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 Nov 2009

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At a glance

  • Drugs Verubulin (Primary)
  • Indications Cancer metastases
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 21 Nov 2009 Planned number of patients changed from 18 to 40 as reported by M.D. Anderson Cancer Center record.
    • 30 Nov 2005 New trial record.

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