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Memantine add-on to Risperidon for Treatment of Negative Symptoms and Cognitive Dysfunction in Patients With Chronic Schizophrenia: Results of a Proof of Concept Study

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Trial Profile

Memantine add-on to Risperidon for Treatment of Negative Symptoms and Cognitive Dysfunction in Patients With Chronic Schizophrenia: Results of a Proof of Concept Study

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 13 Aug 2019

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At a glance

  • Drugs Memantine (Primary) ; Risperidone
  • Indications Schizophrenia
  • Focus Proof of concept; Therapeutic Use
  • Most Recent Events

    • 07 Aug 2019 Primary endpoint (Changes in PANSS negative subscore between memantine and placebo treatment during trial) has been met as per results published in the Pharmacopsychiatry
    • 07 Aug 2019 Results assessing effects of on cognition and negative symptoms of a 6- or 24-week memantine add-on treatment to risperidone in patients with acute or chronic schizophrenia published in the Pharmacopsychiatry
    • 17 Oct 2013 Status changed from active, no longer recruiting to discontinued as reported by ClinicalTrials.gov.

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