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A Phase III Multicentre, Double Blind, Placebo-controlled, Parallel Group 52-week Study to Assess the Efficacy and Safety of 2 Dose Regimens of Lyophilised CDP870 as Additional Medication to Methotrexate in the Treatment of Signs and Symptoms and Preventing Structural Damage in Patients With Active Rheumatoid Arthritis Who Have an Incomplete Response to Methotrexate

Trial Profile

A Phase III Multicentre, Double Blind, Placebo-controlled, Parallel Group 52-week Study to Assess the Efficacy and Safety of 2 Dose Regimens of Lyophilised CDP870 as Additional Medication to Methotrexate in the Treatment of Signs and Symptoms and Preventing Structural Damage in Patients With Active Rheumatoid Arthritis Who Have an Incomplete Response to Methotrexate

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 21 Jan 2022

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At a glance

  • Drugs Certolizumab pegol (Primary) ; Methotrexate
  • Indications Rheumatoid arthritis
  • Focus Registrational; Therapeutic Use
  • Acronyms RAPID-1; RAPID1
  • Sponsors UCB
  • Most Recent Events

    • 06 Jun 2020 Results pooled analysis of efficacy from 4 trials (RAPID 1, RAPID 2, J-RAPID and RAPID-C), presented at the 21st Annual Congress of the European League Against Rheumatism
    • 06 Jun 2020 Results (N=2970, post hoc analysis to quantify finger joint space width, presented at the 21st Annual Congress of the European League Against Rheumatism
    • 04 Jun 2020 According to an UCB media release, post-hoc analysis results from the pooled studies RAPID 1 (NCT00152386), RAPID 2 (NCT00175877), J-RAPID (NCT00791999) and RAPID-C (NCT02151851) were presented at the Annual European Congress of Rheumatology (EULAR) 2020.
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