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A phase I/II clinical trial to evaluate the safety and immunogenicity of a multiclade HIV-1 DNA plasmid vaccine, VRC-HIVDNA016-00-VP, boosted by a multiclade HIV-1 recombinant adenovirus-5 vector vaccine, VRC-HIVADV014-00-VP, in HIV uninfected adult volunteers in East Africa.

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A phase I/II clinical trial to evaluate the safety and immunogenicity of a multiclade HIV-1 DNA plasmid vaccine, VRC-HIVDNA016-00-VP, boosted by a multiclade HIV-1 recombinant adenovirus-5 vector vaccine, VRC-HIVADV014-00-VP, in HIV uninfected adult volunteers in East Africa.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs VRC-HIVADV014-00-VP (Primary) ; VRC-HIVDNA016-00-VP (Primary)
  • Indications HIV-1 infections
  • Focus Adverse reactions; Pharmacodynamics

    • Most Recent Events

    • 09 Feb 2010 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 11 Jan 2010 Results were published in the Journal of Infectious Diseases.
    • 28 Aug 2008 Status changed from recruiting to active, no longer recruiting, as reported by ClinicalTrials.gov.

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