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A phase I study of regulatory T cell depletion with denileukin diftitox followed by active immunotherapy with autologous dendritic cells infected with CEA-6D expressing fowlpox-tricom [cancer vaccine] in patients with advanced or metastatic malignancies expressing CEA [carcinoembryonic antigen]

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A phase I study of regulatory T cell depletion with denileukin diftitox followed by active immunotherapy with autologous dendritic cells infected with CEA-6D expressing fowlpox-tricom [cancer vaccine] in patients with advanced or metastatic malignancies expressing CEA [carcinoembryonic antigen]

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Cancer vaccine (Primary) ; Denileukin diftitox (Primary)
  • Indications Cancer metastases
  • Focus Adverse reactions

    • Most Recent Events

    • 01 May 2009 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
    • 06 Apr 2008 Status changed from recruiting to in progress, as reported by ClinicalTrials.gov.
    • 16 Jan 2008 The expected completion date for this trial is now 1 Mar 2006.

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