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Randomized phase III trial comparing in a preoperative schedule the result of two concurrent chemoradiation schemes (45 Gy + capecitabine vs 50 Gy + capecitabine - oxaliplatin) on the rate of sterilization of the operative specimen in resectable rectal carcinomas T3-4 N0-2 M0.

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Randomized phase III trial comparing in a preoperative schedule the result of two concurrent chemoradiation schemes (45 Gy + capecitabine vs 50 Gy + capecitabine - oxaliplatin) on the rate of sterilization of the operative specimen in resectable rectal carcinomas T3-4 N0-2 M0.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Capecitabine (Primary) ; Oxaliplatin (Primary)
  • Indications Colorectal cancer; Rectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PRODIGE-2

    • Most Recent Events

    • 12 Sep 2017 Results assessing the impact of Immune response-associated gene polymorphisms on tumor response (n=316) presented at the 42nd European Society for Medical Oncology Congress
    • 06 Jun 2017 Results assessing the impact of gene polymorphisms on tumour response (n=316), presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
    • 18 Dec 2005 New trial record.

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