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Effects of Candesartan Cilexetil (Candesartan) on Diabetic Retinopathy in Type 2 Diabetic Patients With Retinopathy.

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Trial Profile

Effects of Candesartan Cilexetil (Candesartan) on Diabetic Retinopathy in Type 2 Diabetic Patients With Retinopathy.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Dec 2021

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At a glance

  • Drugs Candesartan cilexetil (Primary)
  • Indications Diabetic nephropathies; Diabetic retinopathy; Proteinuria
  • Focus Registrational; Therapeutic Use
  • Acronyms DIRECT; DIRECT-Protect-2
  • Sponsors AstraZeneca

    • Most Recent Events

    • 06 Jul 2021 Results (N=1575) post hoc analysis from two randomized controlled trials, DIRECT-Protect 1 and 2 assessing candesartan on progression of diabetic retinopathy in type 1 and type 2 diabetes published in the Diabetic Medicine
    • 29 Jun 2021 Results of post-hoc analysis assessing the effect of candesartan on the progression of diabetic retinopathy in 783 and 792 randomly chosen subjects from two randomized controlled trials (DIRECT-Protect 1 and DIRECT-Protect 2), presented at the 81st Annual Scientific Sessions of the American Diabetes Association.
    • 24 Sep 2010 Results of an analysis that examined the effects of treatment on microalbuminuria presented at the 46th Annual Meeting of the European Association for the Study of Diabetes

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