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Kronos Early Estrogen Prevention Study (KEEPS)

Trial Profile

Kronos Early Estrogen Prevention Study (KEEPS)

Phase of Trial: Phase IV

Latest Information Update: 17 Apr 2018

At a glance

  • Drugs Conjugated estrogens (Primary) ; Estradiol (Primary) ; Progesterone; Progesterone
  • Indications Atherosclerosis; Menopausal syndrome
  • Focus Therapeutic Use
  • Acronyms KEEPS; KEEPS-CA
  • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 17 Apr 2018 Results (n=75) of a study assessing longitudinal changes in structural brain MRI and global cognitive function 3 years after the end of mHT in KEEPS and the association of these findings with beta amyloid load on PET published in the Neurology
    • 28 Aug 2017 Results (n=670) of ancillary study assessing effects of oral or transdermal estrogen therapy on sexual function in postmenopausal women published in the JAMA Internal Medicine
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