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A randomized, open-label study of the effect of MabThera, with and without fludarabine/cyclophosphamide, on progression-free survival in patients with chronic lymphocytic leukemia.

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Trial Profile

A randomized, open-label study of the effect of MabThera, with and without fludarabine/cyclophosphamide, on progression-free survival in patients with chronic lymphocytic leukemia.

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 04 Jan 2021

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At a glance

  • Drugs Rituximab (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Chronic lymphocytic leukaemia
  • Focus Pharmacogenomic; Registrational; Therapeutic Use
  • Sponsors Roche

    • Most Recent Events

    • 08 Dec 2020 Results of pooled analysis (CLL7, CLL8, CLL10, CLL11 and CLL2M)presented at the 62nd Annual Meeting and Exposition of the American Society of Hematology
    • 29 Aug 2016 Results (n=554) of this and other trial (CLL10) published in the Journal of Clinical Oncology (2016).
    • 08 Dec 2015 Results (pooled analysis of CLL8 and CLL10 studies) presented at the 57th Annual Meeting and Exposition of the American Society of Hematology (n = 635).
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