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A Double Blind Randomization to Letrozole or Placebo for Women Previously Diagnosed With Primary Breast Cancer Completing Five Years of Adjuvant Aromatase Inhibitor Either as Initial Therapy or After Tamoxifen (Including Those in The MA.17 Study).

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A Double Blind Randomization to Letrozole or Placebo for Women Previously Diagnosed With Primary Breast Cancer Completing Five Years of Adjuvant Aromatase Inhibitor Either as Initial Therapy or After Tamoxifen (Including Those in The MA.17 Study).

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Aug 2023

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At a glance

  • Drugs Letrozole (Primary)
  • Indications Early breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 01 Feb 2022 Results (n=1735) devloping a tool for identification of women with limited treatment benefit published in the Breast Cancer Research and Treatment
    • 11 Apr 2021 Results of a secondary analysis of large adjuvant endocrine therapy trials (MA.17, MA.17R and MA.27) quantify the impact of competing risks on estimates of disease recurrence and benefit from therapypublished in the European Journal of Cancer
    • 10 Jan 2017 Planned End Date changed from 1 Nov 2016 to 1 Feb 2017.

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