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A phase 2, open-label, dose escalation study to assess the safety and efficacy of ISIS 301012 as add-on therapy in homozygous familial hypercholesterolemia subjects.

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Trial Profile

A phase 2, open-label, dose escalation study to assess the safety and efficacy of ISIS 301012 as add-on therapy in homozygous familial hypercholesterolemia subjects.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Aug 2016

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At a glance

  • Drugs Mipomersen (Primary)
  • Indications Hyperlipoproteinaemia type II
  • Focus Therapeutic Use
  • Sponsors Genzyme Corporation

    • Most Recent Events

    • 24 Jan 2008 Status changed from in progress to completed (source: ClinicalTrials.gov).
    • 10 Oct 2007 Drug named changed from ISIS 301012 to mipomersen sodium (INN).
    • 16 Feb 2006 New trial record.

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